Photos: Buffalo Bills fall to New England Patriots 29-26
The Buffalo Bills suffer their first loss of the season against conference rival New England Patriots, 29-26 during Week 4 at Highmark Stadium on Sunday, Oct. 4, 2026.
Buffalo Bills running back James Cook III (4) rushes for a touchdown during the second quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills wide receiver Keon Coleman (0) makes a catch while covered by New England Patriots cornerback Marcus Jones (25) during the first quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills running back James Cook III (4) is tripped up by New England Patriots cornerback Marcus Jones (25) during the first quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills wide receiver Keon Coleman (0) celebrates a first down catch during the first quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills wide receiver DJ Moore (2) makes a leaping catch during the first quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills wide receiver Khalil Shakir (10) makes a catch for a first down while covered by New England Patriots cornerback Carlton Davis III (7) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills wide receiver Khalil Shakir (10) makes a catch while covered by New England Patriots cornerback Carlton Davis III (7) and linebacker Darius Muasau (54) during the first quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills quarterback Josh Allen (17) drops back to pass during the first quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills head coach Joe Brady watches the field during the first quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills wide receiver Khalil Shakir (10) makes a catch while covered by New England Patriots cornerback Carlton Davis III (7) during the first quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills quarterback Josh Allen (17) throws a pass during the first quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills running back Ty Johnson (26) makes a catch during the first quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills wide receiver Khalil Shakir (10) makes a catch during the first quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills quarterback Josh Allen (17) throws a pass during the first quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills wide receiver DJ Moore (2) makes a catch along the sideline while covered by New England Patriots cornerback Carlton Davis III (7) during the first quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
The Buffalo Bills host the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills running back James Cook III (4) makes a catch while covered by New England Patriots cornerback Marcus Jones (25) during the first quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
New England Patriots quarterback Drake Maye (10) is hit by Buffalo Bills linebacker Greg Rousseau (15) as he throws a touchdown pass during the first quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
New England Patriots wide receiver Romeo Doubs (87) celebrates his touchdown catch during the first quarter of a game between the Buffalo Bills and the Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
New England Patriots quarterback Drake Maye (10) lines up behind center during the first quarter of a game between the Buffalo Bills and the Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
New England Patriots quarterback Drake Maye (10) looks downfield during the first quarter of a game between the Buffalo Bills and the Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
The Buffalo Bills host the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
New England Patriots head coach Mike Vrabel watches a replay during the first quarter of a game between the Buffalo Bills and the Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
New England Patriots quarterback Drake Maye (10) hands off to running back Rhamondre Stevenson (38) in the end zone during the first quarter of a game between the Buffalo Bills and the Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills tight end Jackson Hawes (85) celebrates good field position after a deep punt during the first quarter of the Bills' game against the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills quarterback Josh Allen (17) throws a pass during the first quarter of a game between the Bills and the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Former Buffalo Bills quarterback Doug Flutie addresses the crowd before the Bills' game against the New England Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026.
Buffalo Bills defensive tackle DeWayne Carter (90) tackles New England Patriots quarterback Drake Maye (10) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills defensive tackle Greg Gaines (97) recovers a fumble during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
Buffalo Bills wide receiver Joshua Palmer (5) can’t hang on to a pass against New England Patriots safety Craig Woodson (4) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
New England Patriots wide receiver Mack Hollins (13) makes a catch against Buffalo Bills cornerback Davison Igbinosun (21) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills wide receiver Khalil Shakir (10) makes a catch against New England Patriots linebacker Christian Elliss (53) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills wide receiver Khalil Shakir (10) makes a catch against New England Patriots safety Craig Woodson (4) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills head coach Joe Brady during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
New England Patriots linebacker Christian Elliss (53) and linebacker Dre'mont Jones (5) tackle Buffalo Bills quarterback Josh Allen (17) as he throws during the second quarter at Highmark Stadium on Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
Buffalo Bills quarterback Josh Allen (17) rushes for a touchdown during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
Buffalo Bills quarterback Josh Allen (17) celebrates his touchdown during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills quarterback Josh Allen (17) celebrates his touchdown during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
Buffalo Bills linebacker Greg Rousseau (15) pursues a fleeing New England Patriots quarterback Drake Maye (10) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills wide receiver Keon Coleman (0) keeps his feet in bounds as he makes a first down catch during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Derek Gee/Buffalo News)
New England Patriots linebacker Christian Elliss (53) recovers a fumble by Buffalo Bills wide receiver Khalil Shakir (10) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Derek Gee/Buffalo News)
Buffalo Bills cornerback Dee Alford (23) intercepts a Drake Maye pass during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills cornerback Dee Alford (23) intercepts a pass intended for New England Patriots wide receiver Romeo Doubs (87) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
Buffalo Bills cornerback Dee Alford (23) celebrates his interception with safety Damar Hamlin (3) and cornerback Davison Igbinosun (21) during the second quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
Singer Natasha Bedingfield performs during halftime at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
New England Patriots quarterback Drake Maye (10) reacts after a hit from Buffalo Bills linebacker Greg Rousseau (15) during the third quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
New England Patriots head coach Mike Vrabel gestures during the third quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
New England Patriots wide receiver Romeo Doubs (87) makes a catch against Buffalo Bills cornerback Maxwell Hairston during the third quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
New England Patriots cornerback Marcus Jones (25) returns a punt against Buffalo Bills wide receiver Greg Dortch (19) during the third quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
Buffalo Bills defensive end Michael Hoecht (55) and linebacker Greg Rousseau (15) hit New England Patriots quarterback Drake Maye (10) as he throws a pass during the third quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Derek Gee/Buffalo News)
Buffalo Bills quarterback Josh Allen (17) throws on the run during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills running back Ty Johnson (26) rushes the ball during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
New England Patriots quarterback Drake Maye (10) scrambles during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Derek Gee/Buffalo News)
Buffalo Bills running back James Cook III (4) finds room against New England Patriots linebacker Robert Spillane (14) during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills quarterback Josh Allen (17) throws a pass during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills wide receiver Keon Coleman (0) makes a catch against New England Patriots cornerback Charles Woods (22) during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
New England Patriots wide receiver Efton Chism III (86) makes a catch over Buffalo Bills cornerback Maxwell Hairston (1) during the fourth quarter at Highmark Stadium on Sunday, Oct. 4, 2026. (Joshua Bessex/Buffalo News)
New England Patriots wide receiver Efton Chism III (86) makes a one-handed catch for a touchdown against Buffalo Bills cornerback Davison Igbinosun (21) during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Derek Gee/Buffalo News)
Buffalo Bills quarterback Josh Allen (17) is pressured by New England Patriots defensive end Dre'mont Jones (5) before throwing an interception during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Derek Gee/Buffalo News)
New England Patriots safety Craig Woodson (4) intercepts a pass intended for Buffalo Bills wide receiver Joshua Palmer (5) during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Derek Gee/Buffalo News)
New England Patriots safety Craig Woodson (4) intercepts a pass intended for Buffalo Bills wide receiver Joshua Palmer (5) during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills quarterback Josh Allen (17) looks up at the scoreboard as he walks off the field after throwing an interception during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills fans are unhappy during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
Buffalo Bills fans are unhappy during the fourth quarter at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
New England Patriots head coach Mike Vrabel and Buffalo Bills head coach Joe Brady shake hands after the Bills’ 29-26 loss to the Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Derek Gee/Buffalo News)
Buffalo Bills tight end Dawson Knox (88) and New England Patriots quarterback Drake Maye (10) shake hands after the Bills’ 29-26 loss to the Patriots at Highmark Stadium in Orchard Park, Sunday, Oct. 4, 2026. (Harry Scull Jr./Buffalo News)
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Lance Lysowski is a news sports reporter for The Buffalo News. He can be reached at llysowski@buffnews.com.
Buffalo Bills fans circle the wagons outside Highmark Stadiums for the Buffalo Bills game against the Los Angeles Chargers in Week 3 of NFL action.
Buffalo Bills players enter Highmark Stadium before the Bills' game against the New England Patriots on Sunday.
Michael Petro is a business reporter for The Buffalo News. He can be reached at mpetro@buffnews.com.
